Trezor Safe 3:Physical buttonsDisplay: Display without touch input
Ledger Flex:Touchscreen
Battery
Trezor Safe 3:No battery
Ledger Flex:Rechargeable
What they have in common
Cryptocurrencies
Multiple cryptocurrencies
Both
Wallet recovery
Recovery phrase
Both
Not fully confirmed
Operating power
Trezor Safe 3:USB power
Ledger Flex:Not recorded
Before you choose
Consider
Trezor Safe 3USB signing on computer or Android; the iPhone app does not let this model approve transactions.
Ledger FlexiPhone connects by Bluetooth. Android connects by USB or Bluetooth. NFC does not replace USB or Bluetooth for ordinary transactions. Cryptocurrency support depends on the app.
Apps and requirements
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Connectivity
Trezor Safe 3
Computer
Trezor SuiteUSBBitcoin / EthereumWindows · macOS · Linux
Setup and signing use the Trezor Suite app on Android 12 or later over USB. Your phone needs USB-C support and a suitable data cable. Check that Suite supports the asset and network you want to use; the Bitcoin-only edition is limited to Bitcoin.
Ledger Flex
Computer
Ledger WalletUSBBitcoin / EthereumWindows · macOS · Linux